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NSJ Bioreagents

SKU:V9274SAF-100UG

Recombinant EGFR / EGF Receptor Antibody (Extracellular domain), 100 ug

Recombinant EGFR / EGF Receptor Antibody (Extracellular domain), 100 ug

Regular price $559.00 USD
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Size

This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Specifications

Catalog No V9274SAF-100UG
Family Primary antibody
Qty 100 ug
Formulation 1 mg/ml in 1X PBS; BSA free, sodium azide free
Format Purified
Clone EGFR/6390R
Host Animal Rabbit
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG
Species Reactivity Human
Application IHC-P
Application Details Immunohistochemistry (FFPE): 1-2ug/ml
Application Note Optimal dilution of the recombinant EGFR antibody should be determined by the researcher.
Localization Cell Surface
Immunogen Amin0 acids 25-645 from the extracellular domain of the human protein were used as the immunogen for the recombinant EGF Receptor antibody.
Purity Protein A/G affinity
Storage Aliquot the recombinant EGFR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This recombinant EGFR antibody is available for research use only.
Uniprot # P00533
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/recombinant-egfr-egf-receptor-antibody-extracellular-domain-egfr6390r-v9274
Title Recombinant EGFR / EGF Receptor Antibody (Extracellular domain)
Description This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
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