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NSJ Bioreagents
SKU:V9272-20UG
Recombinant CD47 Antibody / IAP / Integrin Associated Protein, 20 ug
Recombinant CD47 Antibody / IAP / Integrin Associated Protein, 20 ug
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Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. [UniProt]
Specifications
| Catalog No | V9272-20UG |
|---|---|
| Family | Primary antibody |
| Qty | 20 ug |
| Formulation | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Format | Purified |
| Clone | CD47/6364R |
| Host Animal | Rabbit |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | IHC-P |
| Application Details | Immunohistochemistry (FFPE): 1-2ug/ml |
| Application Note | Optimal dilution of the recombinant CD47 antibody should be determined by the researcher. |
| Localization | Cell surface, cytoplasmic |
| Immunogen | A portion of amino acids 18-135 from the human protein was used as the immunogen for the recombinant CD47 antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the recombinant CD47 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This recombinant CD47 antibody is available for research use only. |
| Uniprot # | Q08722 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/recombinant-cd47-antibody-iap-integrin-associated-protein-cd476364r-v9272 |
| Title | Recombinant CD47 Antibody / IAP / Integrin Associated Protein |
| Description | Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. [UniProt] |
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