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NSJ Bioreagents
SKU:V9263-100UG
EGF Receptor / EGFR Antibody (C-terminal region), 100 ug
EGF Receptor / EGFR Antibody (C-terminal region), 100 ug
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This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
Specifications
| Catalog No | V9263-100UG |
|---|---|
| Family | Primary antibody |
| Qty | 100 ug |
| Formulation | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
| Format | Purified |
| Clone | EGFR/4575 |
| Host Animal | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1, kappa |
| Species Reactivity | Human |
| Application | WB, IHC-P |
| Application Details | Western blot: 2-4ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml |
| Application Note | Optimal dilution of the EGF Receptor antibody should be determined by the researcher. |
| Localization | Cell Surface |
| Immunogen | A portion of amino acids 1163-1191 from the C-terminal region of human EGFR was used as the immunogen for the EGF Receptor antibody. |
| Purity | Protein A/G affinity |
| Storage | Aliquot the EGF Receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This EGF Receptor antibody is available for research use only. |
| Uniprot # | P00533 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/egf-receptor-egfr-antibody-c-terminal-region-egfr4575-v9263 |
| Title | EGF Receptor / EGFR Antibody (C-terminal region) |
| Description | This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas. |
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