NSJ Bioreagents
SKU:RZ1236
Zebrafish Lysozyme Antibody / Lyz, 100 ug
Zebrafish Lysozyme Antibody / Lyz, 100 ug
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Lysozyme is an antimicrobial enzyme that plays a key role in the innate immune system by breaking down bacterial cell walls. In zebrafish, lysozyme is expressed in immune cells such as neutrophils and macrophages and contributes to the early defense against bacterial infections.
Lysozyme functions by cleaving the glycosidic bonds in peptidoglycan, a major structural component of bacterial cell walls, particularly in gram positive bacteria. This activity leads to bacterial lysis and supports the clearance of pathogens from the host. In zebrafish, lysozyme genes are expressed during embryogenesis and are upregulated in response to infection or immune stimulation, making them important markers of immune activation.
Zebrafish lysozyme is highly conserved with its mammalian counterparts and is commonly used in research focused on host pathogen interactions, inflammation, and immune system development. It is also a valuable tool for studying the effects of genetic mutations, environmental exposures, or pharmaceuticals on immune responses in vivo.
Because of the transparency of zebrafish embryos and the availability of immune cell specific transgenic lines, lysozyme expression can be visualized and quantified in real time during infection and inflammation models. This makes zebrafish lysozyme a widely used marker in developmental immunology and disease research.
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