Zebrafish Fli1 Antibody / Friend leukemia integration 1 transcription factor, 100 ug

Friend leukemia integration 1 transcription factor (FLI1),also known as transcription factor ERGB,is a protein that in humans is encoded by the FLI1 gene,which is a proto-oncogene. It is mapped to 11q24.3. This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22,which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.