PHF8 Antibody / PHD finger protein 8, 100 ul

PHD finger protein 8 (PHF8) is a histone demethylase that specifically removes methyl groups from lysine residues on histone H3, including H3K9me2 and H3K27me2. By altering chromatin structure, PHF8 regulates transcriptional activation and repression, influencing processes such as cell cycle progression, neuronal development, and differentiation.

PHF8 contains a PHD finger domain that recognizes specific histone modifications, allowing it to target distinct genomic loci. Mutations in PHF8 have been associated with X-linked intellectual disability and craniofacial anomalies. Research on PHF8 provides valuable insights into epigenetic regulation, development, and disease mechanisms.

Using a high-quality PHF8 antibody enables precise detection in applications such as western blot, immunohistochemistry, and chromatin immunoprecipitation. A PHF8 antibody from NSJ Bioreagents ensures reproducibility and sensitivity for studies in epigenetics, transcriptional regulation, and developmental biology. Selecting the right PHF8 antibody is essential for generating consistent and meaningful results.