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NSJ Bioreagents
SKU:RQ8698
AKAP8 Antibody / A-kinase anchor protein 8 / AKAP 95, 100 ul
AKAP8 Antibody / A-kinase anchor protein 8 / AKAP 95, 100 ul
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AKAP8 is an anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase. Acts as an anchor for a PKA-signaling complex onto mitotic chromosomes, which is required for maintenance of chromosomes in a condensed form throughout mitosis. Recruits condensin complex subunit NCAPD2 to chromosomes required for chromatin condensation; the function appears to be independent from PKA-anchoring. [UniProt]
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