IST1 Antibody / CHMP8, 100 ug

IST1 homolog, also called CHMP8 and Charged multivesicular body protein 8, is a protein that in humans is encoded by the IST1 gene. This gene encodes a protein with MIT-interacting motifs that interacts with components of endosomal sorting complexes required for transport (ESCRT). ESCRT functions in vesicle budding, such as that which occurs during membrane abscission in cytokinesis. There is a pseudogene for this gene on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.