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NSJ Bioreagents
SKU:F50653-0.4ML
MUSK Antibody, 0.4ml
MUSK Antibody, 0.4ml
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MuSK activates signaling cascades responsible for many aspects of synapse formation, including the organization of the postsynaptic membrane, synapse-specific transcription, and presynaptic differentiation. MuSK also mediates agrin-induced aggregation of acetylcholine receptors at the mature vertebrate neuromuscular junction and also during synapse formation. It has been shown that a majority of AChR Ab-seronegative myasthenia gravis patients possess serum autoantibodies against MuSK.
Specifications
| Catalog No | F50653-0.4ML |
|---|---|
| Family | Primary antibody |
| Qty | 0.4ml |
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human, Mouse |
| Application | WB, FACS, IF, ELISA |
| Application Details | Western blot: 1:1000,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50 |
| Application Note | Titration of the MUSK antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Status | Available |
| PDF Link | Product Data Sheet (PDF) |
| Limitation | This MUSK antibody is available for research use only. |
| Uniprot # | O15146 |
| Purity | Purified |
| Immunogen | This MUSK antibody was produced from rabbits immunized with human MUSK recombinant protein. |
| Storage | Aliquot the MUSK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Title | MUSK Antibody |
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