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NSJ Bioreagents
SKU:F50602-0.4ML
HER2 Antibody / ErbB2, 0.4ml
HER2 Antibody / ErbB2, 0.4ml
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ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues.<br><br>For broad detection of HER2 (ErbB2) as a receptor tyrosine kinase, see our <a href=../tds/her-2-antibody-erbb2-erbb23257-v7563>HER2 antibody</a>.
Specifications
| Catalog No | F50602-0.4ML |
|---|---|
| Family | Primary antibody |
| Qty | 0.4ml |
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Application | WB, IHC, FACS, IF, ELISA |
| Application Details | Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50 |
| Application Note | Titration of the HER2 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Status | Available |
| PDF Link | Product Data Sheet (PDF) |
| Limitation | This HER2 antibody is available for research use only. |
| Uniprot # | P04626 |
| Purity | Purified |
| Immunogen | This HER2 antibody was produced from rabbits immunized with human recombinant ErbB2 protein. |
| Storage | Aliquot the HER2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Title | HER2 Antibody / ErbB2 |
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