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NSJ Bioreagents
SKU:F50188-0.08ML
AMPK alpha 1 Antibody / PRKAA1, 0.08ml
AMPK alpha 1 Antibody / PRKAA1, 0.08ml
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AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. It appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. AMPK alpha 1, a member of the Ser/Thr protein kinase family, is a catalytic subunit of AMPK.
Specifications
| Catalog No | F50188-0.08ML |
|---|---|
| Family | Primary antibody |
| Qty | 0.08ml |
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human, Mouse |
| Application | WB, ELISA |
| Application Details | Western blot: 1:1000 |
| Application Note | Titration of the AMPK antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Status | Available |
| PDF Link | Product Data Sheet (PDF) |
| Limitation | This AMPK antibody is available for research use only. |
| Uniprot # | Q13131 |
| Purity | Purified |
| Immunogen | A portion of amino acids 479-510 from the human protein was used as the immunogen for this AMPK antibody. |
| Storage | Aliquot the AMPK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Title | AMPK alpha 1 Antibody / PRKAA1 |
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