NSJ Bioreagents
SKU:F49614-0.4ML
PARP1 Antibody, 0.4ml
PARP1 Antibody, 0.4ml
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PARP is a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.<br><br>Additional PARP1 pathway and chromatin-associated DNA repair studies may benefit from our PARP1 antibody page featuring <a href=../tds/parp-antibody-cfd-16-rq5290>recombinant rabbit monoclonal clone CFD-16</a> with knockdown-validated target recognition.
Specifications
| Catalog No | F49614-0.4ML |
|---|---|
| Family | Primary antibody |
| Qty | 0.4ml |
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Predicted Species Reactivity | Mouse |
| Application | WB, FACS, ELISA |
| Application Details | Western blot: 1:1000,Flow Cytometry: 1:10-1:50 |
| Application Note | Titration of the PARP antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Status | Available |
| PDF Link | Product Data Sheet (PDF) |
| Limitation | This PARP antibody is available for research use only. |
| Uniprot # | P09874 |
| Purity | Purified |
| Immunogen | A portion of amino acids 183-214 from the human protein was used as the immunogen for this PARP antibody. |
| Storage | Aliquot the PARP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Title | PARP1 Antibody |
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