NSJ Bioreagents
SKU:F47612-0.08ML
c-Myc Antibody, 0.08ml
c-Myc Antibody, 0.08ml
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MYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of the gene encoding MYC have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Specifications
| Catalog No | F47612-0.08ML |
|---|---|
| Family | Primary antibody |
| Qty | 0.08ml |
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Predicted Species Reactivity | Bovine,Chicken,Mouse,Pig,Rat,Xenopus,Zebrafish |
| Application | WB, IHC, ELISA |
| Application Details | Western blot: 1:1000,IHC (Paraffin): 1:10-1:50 |
| Application Note | Titration of the Myc antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Status | Available |
| PDF Link | Product Data Sheet (PDF) |
| Limitation | This Myc antibody is available for research use only. |
| Uniprot # | P01106 |
| Purity | Antigen affinity |
| Immunogen | A portion of amino acids 36-65 from the human protein was used as the immunogen for this Myc antibody. |
| Storage | Aliquot the Myc antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Title | c-Myc Antibody |
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