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NSJ Bioreagents
SKU:F46149-0.4ML
LC3B Antibody / MAP1LC3B, 0.4ml
LC3B Antibody / MAP1LC3B, 0.4ml
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MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. MAP1LC3B is one of the light chain subunits and can associate with either MAP1A or MAP1B. It is a Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). LC3B plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.
Specifications
| Catalog No | F46149-0.4ML |
|---|---|
| Family | Primary antibody |
| Qty | 0.4ml |
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human, Mouse |
| Predicted Species Reactivity | Bovine |
| Application | IF, ICC, ELISA |
| Application Details | Immunofluorescence: 1:10-1:100,Immunocytochemistry: 1:10-1:50 |
| Application Note | Titration of the LC3B antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Status | Available |
| PDF Link | Product Data Sheet (PDF) |
| Limitation | This LC3B antibody is available for research use only. |
| Uniprot # | Q9GZQ8 |
| Purity | Antigen affinity |
| Immunogen | A portion of amino acids 89-122 from the human protein was used as the immunogen for this LC3B antibody. |
| Storage | Aliquot the LC3B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Title | LC3B Antibody / MAP1LC3B |
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