NSJ Bioreagents
SKU:F40415-0.08ML
EGF Receptor / EGFR Antibody, 0.08ml
EGF Receptor / EGFR Antibody, 0.08ml
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The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.<br><br>Explore our <a href=../tds/egfr-antibody-epidermal-growth-factor-receptor-31g7-v2485>EGFR Antibody (31G7)</a> page for a broader view of EGFR expression and extensively validated antibody performance across applications.
Specifications
| Catalog No | F40415-0.08ML |
|---|---|
| Family | Primary antibody |
| Qty | 0.08ml |
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Clone | 51CT78.40.5 |
| Host Animal | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1, k |
| Species Reactivity | Human |
| Application | IHC, FACS, WB, ELISA |
| Application Details | Western blot: 1:2000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50 |
| Application Note | Titration of the EGFR antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Status | Available |
| PDF Link | Product Data Sheet (PDF) |
| Limitation | This EGFR antibody is available for research use only. |
| Uniprot # | P00533 |
| Purity | Purified |
| Immunogen | Purified His-tagged protein fragment was used to produced this monoclonal EGFR antibody. |
| Storage | Aliquot the EGFR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Localization | Cytoplasmic, membranous |
| Title | EGF Receptor / EGFR Antibody |
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