NSJ Bioreagents
SKU:F40405-0.4ML
EGF Receptor / EGFR Antibody, 0.4ml
EGF Receptor / EGFR Antibody, 0.4ml
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The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.<br><br>Explore our <a href=../tds/egfr-antibody-epidermal-growth-factor-receptor-31g7-v2485>EGFR Antibody (31G7)</a> page for a broader view of EGFR expression and extensively validated antibody performance across applications.
Specifications
| Catalog No | F40405-0.4ML |
|---|---|
| Family | Primary antibody |
| Qty | 0.4ml |
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Clone | 688CT33.1.3 |
| Host Animal | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1 |
| Species Reactivity | Human |
| Application | WB, IHC, ELISA |
| Application Details | IHC (Paraffin): 1:25,Western blot: 1:1000 |
| Application Note | Titration of the EGF Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Status | Available |
| PDF Link | Product Data Sheet (PDF) |
| Limitation | This EGF Receptor antibody is available for research use only. |
| Uniprot # | P00533 |
| Purity | Purified |
| Immunogen | A portion of amino acids 1163-1191 from the human protein was used as the immunogen for this EGF Receptor antibody. |
| Storage | Aliquot the EGF Receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Localization | Cytoplasmic, membranous |
| Title | EGF Receptor / EGFR Antibody |
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