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NSJ Bioreagents
SKU:F54436-0.08ML
Cystathionine Beta Synthase Antibody / CBS
Cystathionine Beta Synthase Antibody / CBS
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$205.00 USD
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CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. This protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human, Mouse |
| Application | IF, WB, FACS, IHC-P |
| Application Details | Immunofluorescence: 1:25,Western blot: 1:500-1:2000,Flow cytometry: 1:25 (1x10e6 cells),Immunohistochemistry (FFPE): 1:25 |
| Application Note | The stated application concentrations are suggested starting points. Titration of the Cystathionine Beta Synthase antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Localization | Nuclear, cytoplasmic |
| Immunogen | A portion of amino acids 104-133 from the human protein was used as the immunogen for the Cystathionine Beta Synthase antibody. |
| Purity | Antigen affinity purified |
| Storage | Aliquot the Cystathionine Beta Synthase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This Cystathionine Beta Synthase antibody is available for research use only. |
| Uniprot # | P35520 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/cystathionine-beta-synthase-antibody-cbs-f54436 |
| Title | Cystathionine Beta Synthase Antibody / CBS |
| Description | CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. This protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. |
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