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NSJ Bioreagents

SKU:F47635-0.08ML

CXCR5 Antibody / BLR1 / MDR15

CXCR5 Antibody / BLR1 / MDR15

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This gene was identified as a gene specifically expressed in Burkitt's lymphoma and lymphatic tissues. The protein encoded by this gene is predicted to be a seven transmembrane G protein- coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B-lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of this gene and its mouse conterpart strongly suggest the essential function of this gene in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen. Two alternatively spliced variants of this gene exist.

Specifications

Family Primary antibody
Formulation In 1X PBS, pH 7.4, with 0.09% sodium azide
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Species Reactivity Human
Application WB, ELISA
Application Details Western blot: 1:1000
Application Note Titration of the CXCR5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Immunogen A portion of amino acids 1-30 from the human protein was used as the immunogen for this CXCR5 antibody.
Purity Antigen affinity
Storage Aliquot the CXCR5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This CXCR5 antibody is available for research use only.
Uniprot # P32302
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/cxcr5-antibody-blr1-mdr15-f47635
Title CXCR5 Antibody / BLR1 / MDR15
Description This gene was identified as a gene specifically expressed in Burkitt's lymphoma and lymphatic tissues. The protein encoded by this gene is predicted to be a seven transmembrane G protein- coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B-lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of this gene and its mouse conterpart strongly suggest the essential function of this gene in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen. Two alternatively spliced variants of this gene exist.
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