NSJ Bioreagents
SKU:R31873
CXCL10 Antibody / IP10
CXCL10 Antibody / IP10
Couldn't load pickup availability
C-X-C motif chemokine 10 (CXCL10), also known as Interferon gamma-induced protein 10kDa (IP-10) or small-inducible cytokine B10, is a protein that in humans is encoded by the CXCL10 gene. It is a small cytokine belonging to the CXC chemokine family. The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines. Luster et al. (1987) reported the isolation of an interferon-inducible gene that encodes a 98-amino acid protein called IP10. The chemokine IFN-gamma-inducible protein 10 (IP-10; CXCL10), a CXC chemokine, and its receptor, CXCR3, were found to be overexpressed in lymph node cells of EAMG rats. IP10 inhibits bone marrow colony formation, has antitumor activity in vivo, is a chemoattractant for human monocytes and T cells, and promotes T cell adhesion to endothelial cells.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | WB, ELISA (protein) |
| Application Details | Western blot: 0.1-0.5ug/ml,ELISA: 0.1-0.5ug/ml (human protein tested); request BSA-free format for coating |
| Application Note | Optimal dilution of the CXCL10 antibody should be determined by the researcher. |
| Immunogen | Amino acids 22-98 of human IP10/CXCL10 were used as the immunogen for the CXCL10 antibody. |
| Buffer | Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide |
| Purity | Antigen affinity |
| Storage | After reconstitution, the CXCL10 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This CXCL10 antibody is available for research use only. |
| Uniprot # | P02778 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/cxcl10-antibody-ip10-r31873 |
| Title | CXCL10 Antibody / IP10 |
| Description | C-X-C motif chemokine 10 (CXCL10), also known as Interferon gamma-induced protein 10kDa (IP-10) or small-inducible cytokine B10, is a protein that in humans is encoded by the CXCL10 gene. It is a small cytokine belonging to the CXC chemokine family. The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines. Luster et al. (1987) reported the isolation of an interferon-inducible gene that encodes a 98-amino acid protein called IP10. The chemokine IFN-gamma-inducible protein 10 (IP-10; CXCL10), a CXC chemokine, and its receptor, CXCR3, were found to be overexpressed in lymph node cells of EAMG rats. IP10 inhibits bone marrow colony formation, has antitumor activity in vivo, is a chemoattractant for human monocytes and T cells, and promotes T cell adhesion to endothelial cells. |
Share
