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NSJ Bioreagents
SKU:R30201
Cx43 Antibody / Connexin 43
Cx43 Antibody / Connexin 43
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$449.00 USD
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Connexin 43 (Cx43), also called GAP Junction Protein, alpha, is a member of the connexin gene family and is abundantly expressed in the heart and liver. Connexin 43, the major protein of gap junctions in the heart, is targeted by several protein kinases that regulate myocardial cell-cell coupling. Cx43 also plays a critical role in the physiology of hearing, presumably by participating in the recycling of potassium to the cochlear endolymph.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human (1), Mouse, Rat |
| Application | WB, IHC-P, IHC-F |
| Application Details | Western blot: 0.5-1ug/ml,IHC (FFPE): 0.5-1ug/ml,IHC (Frozen): 0.5-1ug/ml |
| Application Note | Titration of the Cx43 antibody may be required due to differences in protocols and secondary/substrate sensitivity.<br><br>1.Suitability for western blot testing of human samples is still being determined. |
| Localization | Cytoplasm, plasma membrane |
| Immunogen | Amino acids 351-367 (HELQPLAIVDQRPSSRA-human) were used as the immunogen for this Cx43 antibody (100% conserved in mouse and rat). |
| Buffer | Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal |
| Purity | Antigen affinity |
| Storage | The lyophilized Cx43 antibody can be stored at 4oC to -20oC. After reconstitution, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This Cx43 antibody is available for research use only. |
| Uniprot # | P17302 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/cx43-antibody-connexin-43-r30201 |
| Title | Cx43 Antibody / Connexin 43 |
| Description | Connexin 43 (Cx43), also called GAP Junction Protein, alpha, is a member of the connexin gene family and is abundantly expressed in the heart and liver. Connexin 43, the major protein of gap junctions in the heart, is targeted by several protein kinases that regulate myocardial cell-cell coupling. Cx43 also plays a critical role in the physiology of hearing, presumably by participating in the recycling of potassium to the cochlear endolymph. |
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