• Western blot testing of 1) rat spleen, 2) rat lung, 3) rat thymus, 4) mouse lung, 5) human SW620 lysate with Cullin 1 antibody. Predicted/observed molecular weight ~90 kDa.
1 1

NSJ Bioreagents

R32221

Cullin 1 Antibody / CUL1

Cullin 1 Antibody / CUL1

$449.00 USD
$449.00 USD
Sale Sold out
Shipping calculated at checkout.
Size

Cullin 1, also known as CUL1, is a human protein and gene from cullin family. This protein plays an important role in protein degradation and protein ubiquitination. This is an essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. Human cullin 1, but not the other closely related cullins 2, 3, 4A, and 5, selectively interacts with human SKP1.

Specifications

Family Primary antibody
Formulation 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Species Reactivity Human, Mouse, Rat
Application WB
Application Details Western blot: 0.1-0.5ug/ml
Application Note Optimal dilution of the Cullin 1 antibody should be determined by the researcher.
Localization Nuclear, cytoplasmic
Immunogen Amino acids 457-770 of human Cullin 1 were used as the immunogen for the Cullin 1 antibody.
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Purity Antigen affinity
Storage After reconstitution, the Cullin 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitation This Cullin 1 antibody is available for research use only.
Uniprot # Q13616
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/cullin-1-antibody-cul1-r32221
Title Cullin 1 Antibody / CUL1
Description Cullin 1, also known as CUL1, is a human protein and gene from cullin family. This protein plays an important role in protein degradation and protein ubiquitination. This is an essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. Human cullin 1, but not the other closely related cullins 2, 3, 4A, and 5, selectively interacts with human SKP1.
View full details