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NSJ Bioreagents
SKU:F40094-0.08ML
CRFR2D Antibody / CRHR2
CRFR2D Antibody / CRHR2
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Liaw et al. (1996) [PubMed 8536644] stated that there are 2 G protein-coupled corticotropin-releasing hormone (CRH; MIM 122560) receptors, CRHR1 (MIM 122561) and CRHR2, which they termed the CRF2 receptor. CRH is a 41-amino acid peptide synthesized in the hypothalamus that is the principal neuroregulator of the hypothalamic-pituitary-adrenocortical axis and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Application | WB, IHC, FACS, ELISA |
| Application Details | Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50 |
| Application Note | Titration of the CRFR2D antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Immunogen | This CRFR2D antibody was produced from rabbits immunized with a KLH conjugated synthetic peptide selected from the human CRFR2D. |
| Purity | Antigen affinity |
| Storage | Aliquot the CRFR2D antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This CRFR2D antibody is available for research use only. |
| Uniprot # | Q13324 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/crfr2d-antibody-crhr2-f40094 |
| Title | CRFR2D Antibody / CRHR2 |
| Description | Liaw et al. (1996) [PubMed 8536644] stated that there are 2 G protein-coupled corticotropin-releasing hormone (CRH; MIM 122560) receptors, CRHR1 (MIM 122561) and CRHR2, which they termed the CRF2 receptor. CRH is a 41-amino acid peptide synthesized in the hypothalamus that is the principal neuroregulator of the hypothalamic-pituitary-adrenocortical axis and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. |
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