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NSJ Bioreagents
SKU:RQ8047
CREB-2 Antibody / ATF4
CREB-2 Antibody / ATF4
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ATF4, Activating Transcription Factor 4, is also known as Cyclic AMP-responsive element-binding protein 2 (CREB-2). ATF4/CREB-2 belongs to the large ATF/CREB family of transcription factors which bind DNA via their basic region and dimerize via their leucine zipper domain to form a variety of homo- and heterodimers to regulate gene transcription. Unlike CREB, which activates transcription from CRE-containing promoters, CREB-2 functions as a specific repressor of CRE-dependent transcription.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human, Mouse, Rat |
| Application | WB, IF, FACS, Direct ELISA |
| Application Details | Western blot: 0.5-1ug/ml,Immunofluorescence: 5ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml |
| Application Note | Optimal dilution of the CREB-2 antibody should be determined by the researcher. |
| Localization | Nuclear, cytoplasmic, cell membrane |
| Immunogen | E. coli-derived recombinant human protein (amino acids E10-E210) was used as the immunogen for the CREB-2 antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| Purity | Antigen affinity purified |
| Storage | After reconstitution, the CREB-2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This CREB-2 antibody is available for research use only. |
| Uniprot # | P18848 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/creb-2-antibody-atf4-rq8047 |
| Title | CREB-2 Antibody / ATF4 |
| Description | ATF4, Activating Transcription Factor 4, is also known as Cyclic AMP-responsive element-binding protein 2 (CREB-2). ATF4/CREB-2 belongs to the large ATF/CREB family of transcription factors which bind DNA via their basic region and dimerize via their leucine zipper domain to form a variety of homo- and heterodimers to regulate gene transcription. Unlike CREB, which activates transcription from CRE-containing promoters, CREB-2 functions as a specific repressor of CRE-dependent transcription. |
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