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NSJ Bioreagents
SKU:R30437
Connexin 40 Antibody
Connexin 40 Antibody
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$449.00 USD
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Connexin proteins oligomerize to form intercellular channels, called gap junctions, through which ions and small molecules move between adjacent cells. Connexin 40(Gap junction alpha-5 protein) is a protein that in humans is encoded by the GJA5 gene.This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human, Mouse, Rat |
| Application | WB, IHC-P |
| Application Details | Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml |
| Application Note | The stated application concentrations are suggested starting amounts. Titration of the Connexin 40 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Immunogen | An amino acid sequence from the C-terminus of human Connexin 40/GJA5 (KRRLSKASSKARSDDLSV) was used as the immunogen for this Connexin 40 antibody (100% homologous in human, mouse and rat). |
| Buffer | Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal |
| Purity | Antigen affinity |
| Storage | After reconstitution, the Connexin 40 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This Connexin 40 antibody is available for research use only. |
| Uniprot # | P36382 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/connexin-40-antibody-r30437 |
| Title | Connexin 40 Antibody |
| Description | Connexin proteins oligomerize to form intercellular channels, called gap junctions, through which ions and small molecules move between adjacent cells. Connexin 40(Gap junction alpha-5 protein) is a protein that in humans is encoded by the GJA5 gene.This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described. |
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