NSJ Bioreagents
SKU:RQ5382
Collagen VI Antibody / COL6A1
Collagen VI Antibody / COL6A1
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The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [RefSeq]
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA |
| Format | Purified |
| Clone | HGG-3 |
| Host Animal | Rabbit |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Species Reactivity | Human, Mouse, Rat |
| Application | WB |
| Application Details | Western blot: 1:1000-1:2000 |
| Application Note | Optimal dilution of the Collagen VI antibody should be determined by the researcher. |
| Immunogen | A synthetic peptide specific to human Collagen VI / COL6A1 was used as the immunogen for the Collagen VI antibody. |
| Purity | Affinity purified |
| Storage | Store the Collagen VI antibody at -20oC. |
| Limitation | This Collagen VI antibody is available for research use only. |
| Uniprot # | P12109 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/collagen-vi-antibody-col6a1-hgg-3-rq5382 |
| Title | Collagen VI Antibody / COL6A1 |
| Description | The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [RefSeq] |
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