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NSJ Bioreagents
SKU:F54619-0.08ML
COL8A2 Antibody
COL8A2 Antibody
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This gene encodes the alpha 2 chain of type VIII collagen. The protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human, Mouse |
| Application | IHC-P, IF, WB |
| Application Details | Immunohistochemistry (FFPE): 1:25, Immunofluorescence: 1:25, Western blot: 1:500-1:2000 |
| Application Note | The stated application concentrations are suggested starting points. Titration of the COL8A2 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Immunogen | A portion of amino acids 571-599 from the human protein was used as the immunogen for the COL8A2 antibody. |
| Purity | Antigen affinity purified |
| Storage | Aliquot the COL8A2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This COL8A2 antibody is available for research use only. |
| Uniprot # | P25067 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/col8a2-antibody-f54619 |
| Title | COL8A2 Antibody |
| Description | This gene encodes the alpha 2 chain of type VIII collagen. The protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. |
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