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NSJ Bioreagents
SKU:F54600-0.08ML
CNIH2 Antibody
CNIH2 Antibody
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Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors. [UniProt]
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Application | WB, IHC-P, FACS, IF |
| Application Details | Western blot: 1:500-1:2000, Immunohistochemistry (FFPE): 1:25, Flow cytometry: 1:25 (1x10e6 cells), Immunofluorescence: 1:25 |
| Application Note | The stated application concentrations are suggested starting points. Titration of the CNIH2 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Localization | Cytoplasmic |
| Immunogen | A portion of amino acids 31-59 from the human protein was used as the immunogen for the CNIH2 antibody. |
| Purity | Antigen affinity purified |
| Storage | Aliquot the CNIH2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This CNIH2 antibody is available for research use only. |
| Uniprot # | Q6PI25 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/cnih2-antibody-f54600 |
| Title | CNIH2 Antibody |
| Description | Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors. [UniProt] |
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