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NSJ Bioreagents
SKU:RQ6462
CLCN5 Antibody / CIC-5
CLCN5 Antibody / CIC-5
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The CLCN5 gene encodes the chloride channel Cl-/H+ exchanger ClC-5. This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human, Mouse, Rat |
| Application | WB, Direct ELISA |
| Application Details | Western blot: 1-2ug/ml,Direct ELISA: 0.1-0.5ug/ml |
| Application Note | Optimal dilution of the CLCN5 antibody should be determined by the researcher. |
| Immunogen | An E. coli-derived human protein (amino acids R100-S756) was used as the immunogen for the CLCN5 antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| Purity | Affinity purified |
| Storage | After reconstitution, the CLCN5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This CLCN5 antibody is available for research use only. |
| Uniprot # | P51795 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/clcn5-antibody-cic-5-rq6462 |
| Title | CLCN5 Antibody / CIC-5 |
| Description | The CLCN5 gene encodes the chloride channel Cl-/H+ exchanger ClC-5. This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene. |
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