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NSJ Bioreagents
SKU:RQ5047
CK1 Antibody / Cytokeratin 1 / KRT1
CK1 Antibody / Cytokeratin 1 / KRT1
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Cytokeratin 1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. [RefSeq]
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA |
| Format | Purified |
| Clone | GBH-11 |
| Host Animal | Rabbit |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | WB |
| Application Details | Western blot: 1:5000-1:20000 |
| Application Note | Optimal dilution of the CK1 antibody should be determined by the researcher. |
| Immunogen | A synthetic peptide specific to human Cytokeratin 1 / KRT1 was used as the immunogen for the CK1 antibody. |
| Purity | Affinity purified |
| Storage | Store the CK1 antibody at -20oC. |
| Limitation | This CK1 antibody is available for research use only. |
| Uniprot # | P04264 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/ck1-antibody-cytokeratin-1-krt1-gbh-11-rq5047 |
| Title | CK1 Antibody / Cytokeratin 1 / KRT1 |
| Description | Cytokeratin 1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. [RefSeq] |
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