NSJ Bioreagents
SKU:RQ7700
Citrin Antibody / ARALAR2 / SLC25A13
Citrin Antibody / ARALAR2 / SLC25A13
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Citrin also known as solute carrier family 25, member 13 (also called Citrin and ARALAR-related gene 2) is a protein which in humans is encoded by the SLC25A13 gene. This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human, Rat |
| Application | WB, IHC-P, IF, FACS, Direct ELISA |
| Application Details | Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Immunofluorescence: 5ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml |
| Application Note | Optimal dilution of the Citrin antibody should be determined by the researcher. |
| Localization | Cytoplasmic |
| Immunogen | E. coli-derived recombinant human protein (amino acids M1-A643) was used as the immunogen for the Citrin antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| Purity | Antigen affinity purified |
| Storage | After reconstitution, the Citrin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This Citrin antibody is available for research use only. |
| Uniprot # | Q9UJS0 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/citrin-antibody-aralar2-slc25a13-rq7700 |
| Title | Citrin Antibody / ARALAR2 / SLC25A13 |
| Description | Citrin also known as solute carrier family 25, member 13 (also called Citrin and ARALAR-related gene 2) is a protein which in humans is encoded by the SLC25A13 gene. This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene. |
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