NSJ Bioreagents
SKU:RQ8908
CIRBP Antibody / Cold-inducible RNA-binding protein
CIRBP Antibody / Cold-inducible RNA-binding protein
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Cold-inducible RNA-binding protein (CIRBP) is a stress-response protein that binds to RNA and modulates mRNA stability and translation. It is upregulated in response to mild hypothermia, ultraviolet radiation, and other cellular stressors, helping to regulate gene expression under challenging environmental conditions. <p>CIRBP plays roles in cell proliferation, circadian rhythm regulation, and protection against apoptosis. It has been implicated in processes such as spermatogenesis, inflammation, and tumor progression. Altered CIRBP expression or function can influence cellular stress adaptation and disease development, making it a valuable target for molecular and biomedical research. <p>Using a high-quality CIRBP antibody allows precise detection in applications such as western blot, immunohistochemistry, and immunofluorescence. A CIRBP antibody from NSJ Bioreagents ensures reproducibility and sensitivity for studies in stress response biology, RNA regulation, and disease mechanisms. Selecting the right CIRBP antibody is essential for generating consistent and reliable experimental results.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA |
| Format | Purified |
| Clone | 26C38 |
| Host Animal | Rabbit |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | WB, IHC-P |
| Application Details | Western blot: 1:500,Immunohistochemistry (FFPE): 1:50 |
| Application Note | Optimal dilution of the CIRBP antibody should be determined by the researcher. |
| Localization | Nuclear, cytoplasmic |
| Immunogen | A peptide sequence specific to Cold-inducible RNA-binding protein was used as the immunogen for the CIRBP antibody. |
| Purity | Affinity chromatography |
| Storage | After reconstitution, the CIRBP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This CIRBP antibody is available for research use only. |
| Uniprot # | Q14011 |
| Status | Available |
| PDF Link | http://www.nsjbio.com/tds-pdf/cirbp-antibody-cold-inducible-rna-binding-protein-rq8908 |
| Title | CIRBP Antibody / Cold-inducible RNA-binding protein |
| Description | Cold-inducible RNA-binding protein (CIRBP) is a stress-response protein that binds to RNA and modulates mRNA stability and translation. It is upregulated in response to mild hypothermia, ultraviolet radiation, and other cellular stressors, helping to regulate gene expression under challenging environmental conditions. <p>CIRBP plays roles in cell proliferation, circadian rhythm regulation, and protection against apoptosis. It has been implicated in processes such as spermatogenesis, inflammation, and tumor progression. Altered CIRBP expression or function can influence cellular stress adaptation and disease development, making it a valuable target for molecular and biomedical research. <p>Using a high-quality CIRBP antibody allows precise detection in applications such as western blot, immunohistochemistry, and immunofluorescence. A CIRBP antibody from NSJ Bioreagents ensures reproducibility and sensitivity for studies in stress response biology, RNA regulation, and disease mechanisms. Selecting the right CIRBP antibody is essential for generating consistent and reliable experimental results. |
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