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NSJ Bioreagents
SKU:R32968
CHX10 Antibody / VSX2
CHX10 Antibody / VSX2
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Visual system homeobox 2 is a protein that in humans is encoded by the VSX2 gene. This gene encodes a homeobox protein originally described as a retina-specific transcription factor. Mutations in this gene are associated with microphthalmia, cataracts and iris abnormalities. In situ hybridization to human fetal retinal sections detected CHX10 expression in retinal neuroblasts at all stages examined. Human CHX10 is expressed in progenitor cells of the developing neuroretina and in the inner nuclear layer of the mature retina.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Mouse |
| Predicted Species Reactivity | Human |
| Application | WB |
| Application Details | Western Blot: 0.5-1ug/ml |
| Application Note | Optimal dilution of the CHX10 antibody should be determined by the researcher. |
| Immunogen | A recombinant human protein corresponding to amino acids A249-A361 was used as the immunogen for the CHX10 antibody. |
| Buffer | Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide |
| Purity | Antigen affinity |
| Storage | After reconstitution, the CHX10 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This CHX10 antibody is available for research use only. |
| Uniprot # | P58304 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/chx10-antibody-vsx2-r32968 |
| Title | CHX10 Antibody / VSX2 |
| Description | Visual system homeobox 2 is a protein that in humans is encoded by the VSX2 gene. This gene encodes a homeobox protein originally described as a retina-specific transcription factor. Mutations in this gene are associated with microphthalmia, cataracts and iris abnormalities. In situ hybridization to human fetal retinal sections detected CHX10 expression in retinal neuroblasts at all stages examined. Human CHX10 is expressed in progenitor cells of the developing neuroretina and in the inner nuclear layer of the mature retina. |
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