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NSJ Bioreagents

SKU:F54079-0.05ML

CH25H Antibody (N-Terminal Region)

CH25H Antibody (N-Terminal Region)

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Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25- hydroxycholesterol by macrophages may play a role in Leydig cell differentiation. [UniProt]

Specifications

Family Primary antibody
Formulation In 1X PBS, pH 7.4, with 0.09% sodium azide
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Species Reactivity Human, Mouse
Predicted Species Reactivity Pig
Application WB
Application Details Western blot: 1:1000-1:2000
Application Note The stated application concentrations are suggested starting points. Titration of the CH25H antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Immunogen A portion of amino acids 47-76 from human CH25H was used as the immunogen for the CH25H antibody.
Purity Antigen affinity
Storage Aliquot the CH25H antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This CH25H antibody is available for research use only.
Uniprot # O95992
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/ch25h-antibody-n-terminal-region-f54079
Title CH25H Antibody (N-Terminal Region)
Description Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25- hydroxycholesterol by macrophages may play a role in Leydig cell differentiation. [UniProt]
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