NSJ Bioreagents
SKU:R31127
CETP Antibody / Cholesteryl Ester Transfer Protein
CETP Antibody / Cholesteryl Ester Transfer Protein
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Cholesteryl Ester Transfer Protein Plasma, is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. CETP is also known as lipid transfer protein I(Day et al., 1994). Sparkes et al.(1987) used a CETP probe against DNA from a human/mouse somatic cell hybrid panel to assign the gene to chromosome 16. Because the role of CETP in atherosclerosis remained unclear, Okamoto et al.(2000) attempted to develop a potent, specific inhibitor. One inhibitor, JTT-705, forms a disulfide bond with CETP and increases high density lipoprotein (HDL) cholesterol, decreases non-HDL cholesterol, and inhibits the progression of atherosclerosis in rabbits.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | WB |
| Application Details | Western blot: 0.5-1ug/ml |
| Application Note | The stated application concentrations are suggested starting amounts. Titration of the CETP antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Immunogen | An amino acid sequence from the C-terminus of human Cholesteryl Ester Transfer Protein Plasma (PRPDQQHSVAYTFEE) was used as the immunogen for this CETP antibody. |
| Buffer | Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal |
| Purity | Antigen affinity |
| Storage | After reconstitution, the CETP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This CETP antibody is available for research use only. |
| Uniprot # | P11597 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/cetp-antibody-cholesteryl-ester-transfer-protein-r31127 |
| Title | CETP Antibody / Cholesteryl Ester Transfer Protein |
| Description | Cholesteryl Ester Transfer Protein Plasma, is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. CETP is also known as lipid transfer protein I(Day et al., 1994). Sparkes et al.(1987) used a CETP probe against DNA from a human/mouse somatic cell hybrid panel to assign the gene to chromosome 16. Because the role of CETP in atherosclerosis remained unclear, Okamoto et al.(2000) attempted to develop a potent, specific inhibitor. One inhibitor, JTT-705, forms a disulfide bond with CETP and increases high density lipoprotein (HDL) cholesterol, decreases non-HDL cholesterol, and inhibits the progression of atherosclerosis in rabbits. |
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