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NSJ Bioreagents
SKU:F51744-0.08ML
CEBPA Antibody
CEBPA Antibody
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$205.00 USD
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CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. This protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human, Mouse |
| Predicted Species Reactivity | Bovine, Rat |
| Application | FACS, WB, ELISA |
| Application Details | Western blot: 1:1000,Flow Cytometry: 1:10-1:50 |
| Application Note | Titration of the CEBPA antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Immunogen | A portion of amino acids 304-330 from the human protein was used as the immunogen for this CEBPA antibody. |
| Purity | Antigen affinity |
| Storage | Aliquot the CEBPA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This CEBPA antibody is available for research use only. |
| Uniprot # | P49715 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/cebpa-antibody-f51744 |
| Title | CEBPA Antibody |
| Description | CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. This protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells. |
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