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NSJ Bioreagents
SKU:RQ6165
CDK12 Antibody / Cyclin-dependent kinase 12
CDK12 Antibody / Cyclin-dependent kinase 12
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$449.00 USD
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CDK12 (Cyclin-dependent kinase 12) is a protein kinase that in humans is encoded by the CDK12 gene. This enzyme is a member of cyclin-dependent kinase protein family. CDK12 forms protein complexes with cyclin K (CCNK). The CDK12-CCNK complex acts at the level of RNA polymerase II (RNAPII) to regulate expression of long complex genes, several of which have roles in DNA maintenance and repair.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | WB, IF, FACS, IHC-P, IP, Direct ELISA |
| Application Details | Western blot: 1-2ug/ml,Immunofluorescence: 5ug/ml,Flow cytometry: 1-3ug/million cells,Immunohistochemistry (FFPE): 2-5ug/ml,Direct ELISA: 0.1-0.5ug/ml,Immunoprecipitation: 2ug antibody/500ug lysate |
| Application Note | Optimal dilution of the CDK12 antibody should be determined by the researcher. |
| Localization | Nuclear |
| Immunogen | A human recombinant partial protein (amino acids Q1147-N1439) was used as the immunogen for the CDK12 antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| Purity | Affinity purified |
| Storage | After reconstitution, the CDK12 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This CDK12 antibody is available for research use only. |
| Uniprot # | Q9NYV4 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/cdk12-antibody-cyclin-dependent-kinase-12-rq6165 |
| Title | CDK12 Antibody / Cyclin-dependent kinase 12 |
| Description | CDK12 (Cyclin-dependent kinase 12) is a protein kinase that in humans is encoded by the CDK12 gene. This enzyme is a member of cyclin-dependent kinase protein family. CDK12 forms protein complexes with cyclin K (CCNK). The CDK12-CCNK complex acts at the level of RNA polymerase II (RNAPII) to regulate expression of long complex genes, several of which have roles in DNA maintenance and repair. |
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