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NSJ Bioreagents
SKU:F52228-0.08ML
CDH1 Antibody
CDH1 Antibody
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$205.00 USD
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Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Clone | 813CT11.1.3 |
| Host Animal | Mouse |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1, k |
| Species Reactivity | Human, Mouse |
| Application | IHC, WB, ELISA |
| Application Details | IHC (Paraffin): 1:25,Western blot: 1:1000 |
| Application Note | Titration of the CDH1 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Localization | Cytoplasmic, membranous |
| Immunogen | Purified His-tagged protein was used to produced this monoclonal CDH1 antibody. |
| Purity | Purified |
| Storage | Aliquot the CDH1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This CDH1 antibody is available for research use only. |
| Uniprot # | P12830 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/cdh1-antibody-813ct1113-f52228 |
| Title | CDH1 Antibody |
| Description | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production. |
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