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NSJ Bioreagents
SKU:F54262-0.08ML
CDC73 Antibody
CDC73 Antibody
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$205.00 USD
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CDC73 encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Application | WB, IHC-P, FACS, IF |
| Application Details | Western blot: 1:1000-1:2000,Immunohistochemistry (FFPE): 1:25,Flow cytometry: 1:25 (1x10e6 cells),Immunofluorescence: 1:25 |
| Application Note | The stated application concentrations are suggested starting points. Titration of the CDC73 antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Localization | Nuclear |
| Immunogen | A portion of amino acids 132-161 from the human protein were used as the immunogen for the CDC73 antibody. |
| Purity | Antigen affinity purified |
| Storage | Aliquot the CDC73 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This CDC73 antibody is available for research use only. |
| Uniprot # | Q6P1J9 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/cdc73-antibody-f54262 |
| Title | CDC73 Antibody |
| Description | CDC73 encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. |
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