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NSJ Bioreagents

SKU:F51546-0.08ML

CDC20 Antibody

CDC20 Antibody

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CDC20 is an activating regulatory factor for the APC/C (anaphase promoting complex/cyclosome). It activates the ubiquitination activity of the APC/C. CDC20 confers a strict destruction-box (D-box) dependence on APC. Levels of CDC20, as well as its binding to APC, peak in mitosis and decrease drastically at early G1.

Specifications

Family Primary antibody
Formulation In 1X PBS, pH 7.4, with 0.09% sodium azide
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Species Reactivity Human
Predicted Species Reactivity Pig
Application WB, FACS, ELISA
Application Details Western blot: 1:1000,Flow Cytometry: 1:10-1:50
Application Note Titration of the CDC20 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Immunogen A portion of amino acids 57-84 from the human protein was used as the immunogen for this CDC20 antibody.
Purity Antigen affinity
Storage Aliquot the CDC20 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitation This CDC20 antibody is available for research use only.
Uniprot # Q12834
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/cdc20-antibody-f51546
Title CDC20 Antibody
Description CDC20 is an activating regulatory factor for the APC/C (anaphase promoting complex/cyclosome). It activates the ubiquitination activity of the APC/C. CDC20 confers a strict destruction-box (D-box) dependence on APC. Levels of CDC20, as well as its binding to APC, peak in mitosis and decrease drastically at early G1.
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