• Western blot testing of mouse 1) spleen, 2) thymus, 3) lung, 4) RAW264.7, 5) Ana-1 and 6) SP2/0 cell lysate with Cd70 antibody. Predicted molecular weight ~21 kDa but may be observed at up to ~80 kDa due to glycosylation.
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NSJ Bioreagents

RQ6964

Cd70 Antibody

Cd70 Antibody

$449.00 USD
$449.00 USD
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CD70 (Cluster of Differentiation 70) is a protein that in humans is encoded by CD70 gene. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

Specifications

Family Primary antibody
Formulation 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Species Reactivity Mouse, Rat
Application WB, IHC-P, Direct ELISA
Application Details Western blot: 0.5-1 ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Direct ELISA: 0.1-0.5ug/ml
Application Note Optimal dilution of the Cd70 antibody should be determined by the researcher.
Immunogen Recombinant mouse Cd70 protein (amino acids C36-Q191) was used as the immunogen for the Cd70 antibody.
Buffer Lyophilized from 1X PBS with 2% Trehalose
Purity Antigen affinity purified
Storage After reconstitution, the Cd70 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitation This Cd70 antibody is available for research use only.
Uniprot # O55237
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/cd70-antibody-rq6964
Title Cd70 Antibody
Description CD70 (Cluster of Differentiation 70) is a protein that in humans is encoded by CD70 gene. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
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