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NSJ Bioreagents

SKU:RQ7113

CD51 Antibody / Integrin alpha V / ITGAV / Vitronectin Receptor

CD51 Antibody / Integrin alpha V / ITGAV / Vitronectin Receptor

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Integrin alpha-V / CD51 is a protein that in humans is encoded by the ITGAV gene. It is a member of the beta 3 integrin subfamily(cytoadhesins). The human locus for the av gene (VNRA) was previously mapped to the long arm of chromosome 2. Sims et al.(2000) localized the VNRA gene to 2q31. The gene contains 30 exons and spans over 93 kb of genomic DNA. It functions as a receptor for a group of proteins that includes vitronectin, fibrinogen, thrombospondin, and von Willebrand factor.

Specifications

Family Primary antibody
Formulation 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format Antigen affinity purified
Clone 8B10H2
Host Animal Mouse
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b
Species Reactivity Human
Application WB, IF, IHC-P
Application Details Western blot: 0.5-1ug/ml,Immunofluorescence: 5ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml
Application Note Optimal dilution of the CD51 antibody should be determined by the researcher.
Immunogen Recombinant human protein (amino acids H732-D970) was used as the immunogen for the CD51 antibody.
Buffer Lyophilized from 1X PBS with 2% Trehalose
Purity Antigen affinity purified
Storage After reconstitution, the CD51 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitation This CD51 antibody is available for research use only.
Uniprot # P06756
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/cd51-antibody-integrin-alpha-v-itgav-vitronectin-receptor-8b10h2-rq7113
Title CD51 Antibody / Integrin alpha V / ITGAV / Vitronectin Receptor
Description Integrin alpha-V / CD51 is a protein that in humans is encoded by the ITGAV gene. It is a member of the beta 3 integrin subfamily(cytoadhesins). The human locus for the av gene (VNRA) was previously mapped to the long arm of chromosome 2. Sims et al.(2000) localized the VNRA gene to 2q31. The gene contains 30 exons and spans over 93 kb of genomic DNA. It functions as a receptor for a group of proteins that includes vitronectin, fibrinogen, thrombospondin, and von Willebrand factor.
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