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NSJ Bioreagents
SKU:RQ6065
Cd31 Antibody / Pecam-1
Cd31 Antibody / Pecam-1
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CD31 also known as Platelet endothelial cell adhesion molecule (PECAM-1), is a protein that in human is encoded by the PECAM1 gene. Encoded protein is a member of the immunoglobulin superfamily and this gene is mapped to 17q23.3. CD31 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. It is demonstrated that CD31 expression on human PBSCs may positively affect both neutrophil and platelet engraftment. Meanwhile, CD31 is involved in leukocyte migration and angiogenesis, which are key components of venous thrombus resolution.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Mouse, Rat |
| Application | WB, IHC-P, Direct ELISA |
| Application Details | Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Direct ELISA: 0.1-0.5ug/ml |
| Application Note | Optimal dilution of the Cd31 antibody should be determined by the researcher. |
| Immunogen | Recombinant mouse protein (amino acids Q41-E258) was used as the immunogen for the Cd31 antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| Purity | Affinity purified |
| Storage | After reconstitution, the Cd31 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This Cd31 antibody is available for research use only. |
| Uniprot # | Q08481 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/cd31-antibody-pecam-1-rq6065 |
| Title | Cd31 Antibody / Pecam-1 |
| Description | CD31 also known as Platelet endothelial cell adhesion molecule (PECAM-1), is a protein that in human is encoded by the PECAM1 gene. Encoded protein is a member of the immunoglobulin superfamily and this gene is mapped to 17q23.3. CD31 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. It is demonstrated that CD31 expression on human PBSCs may positively affect both neutrophil and platelet engraftment. Meanwhile, CD31 is involved in leukocyte migration and angiogenesis, which are key components of venous thrombus resolution. |
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