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NSJ Bioreagents
SKU:RQ5185
CD3 epsilon Antibody / CD3e
CD3 epsilon Antibody / CD3e
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The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [RefSeq]
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA |
| Format | Purified |
| Clone | EED-3 |
| Host Animal | Rabbit |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Species Reactivity | Human |
| Application | WB |
| Application Details | Western blot: 1:500-1:2000 |
| Application Note | Optimal dilution of the CD3 epsilon antibody should be determined by the researcher. |
| Immunogen | A synthetic peptide specific to human CD3 epsilon / CD3E was used as the immunogen for the CD3 epsilon antibody. |
| Purity | Affinity purified |
| Storage | Store the CD3 epsilon antibody at -20oC. |
| Limitation | This CD3 epsilon antibody is available for research use only. |
| Uniprot # | P07766 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/cd3-epsilon-antibody-cd3e-eed-3-rq5185 |
| Title | CD3 epsilon Antibody / CD3e |
| Description | The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [RefSeq] |
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