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NSJ Bioreagents

SKU:RQ4110

Cd252 Antibody / Ox40l

Cd252 Antibody / Ox40l

Regular price $449.00 USD
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OX40L (TNFSF4, CD252) is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. This gene encodes a cytokine of the tumor necrosis factor (TNF) ligand family. The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells. Polymorphisms in this gene have been associated with Sjogren's syndrome and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.

Specifications

Family Primary antibody
Formulation 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Species Reactivity Mouse, Rat
Application WB, IHC-P
Application Details Western Blot: 0.5-1ug/ml,Immunohistochemistry: 1-2ug/ml
Application Note Optimal dilution of the Cd252 antibody should be determined by the researcher.
Localization Membrane, cytoplasm
Immunogen A recombinant mouse partial protein corresponding to amino acids Q49-L198 was used as the immunogen for the Cd252 antibody.
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Purity Antigen affinity purified
Storage After reconstitution, the Cd252 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitation This Cd252 antibody is available for research use only.
Uniprot # P43488
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/cd252-antibody-ox40l-rq4110
Title Cd252 Antibody / Ox40l
Description OX40L (TNFSF4, CD252) is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. This gene encodes a cytokine of the tumor necrosis factor (TNF) ligand family. The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells. Polymorphisms in this gene have been associated with Sjogren's syndrome and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.
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