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NSJ Bioreagents
SKU:RQ4615
CD137 Antibody / 4-1BB
CD137 Antibody / 4-1BB
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$449.00 USD
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CD137 is a member of the tumor necrosis factor (TNF) receptor family. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Mouse |
| Application | WB, ELISA (Capture) |
| Application Details | Western blot: 0.5-1ug/ml,ELISA (Capture): 1-5ug/ml (mouse recombinant protein) |
| Application Note | Optimal dilution of the CD137 antibody should be determined by the researcher. |
| Immunogen | Amino acids V24-L187 from the mouse protein were used as the immunogen for the CD137 antibody. |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide |
| Purity | Antigen affinity purified |
| Storage | After reconstitution, the CD137 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This CD137 antibody is available for research use only. |
| Uniprot # | P20334 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/cd137-antibody-4-1bb-rq4615 |
| Title | CD137 Antibody / 4-1BB |
| Description | CD137 is a member of the tumor necrosis factor (TNF) receptor family. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. |
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