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NSJ Bioreagents
SKU:F50002-0.08ML
CD11c Antibody / ITGAX
CD11c Antibody / ITGAX
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ITGAX is the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | In 1X PBS, pH 7.4, with 0.09% sodium azide |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Species Reactivity | Human |
| Application | FACS, IF, WB, IHC, ELISA |
| Application Details | Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50 |
| Application Note | Titration of the CD11c antibody may be required due to differences in protocols and secondary/substrate sensitivity. |
| Localization | Cell surface, cytoplasmic |
| Immunogen | A portion of amino acids 1119-1145 from the human protein was used as the immunogen for this CD11c antibody. |
| Purity | Antigen affinity |
| Storage | Aliquot the CD11c antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles. |
| Limitation | This CD11c antibody is available for research use only. |
| Uniprot # | P20702 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/cd11c-antibody-itgax-f50002 |
| Title | CD11c Antibody / ITGAX |
| Description | ITGAX is the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. |
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