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NSJ Bioreagents
SKU:RQ5468
CD104 Antibody / Integrin beta 4 / ITGB4
CD104 Antibody / Integrin beta 4 / ITGB4
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Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. The ITGB4 gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. [RefSeq]
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA |
| Format | Purified |
| Clone | AAFE-9 |
| Host Animal | Rabbit |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Species Reactivity | Human, Mouse |
| Application | WB |
| Application Details | Western blot: 1:500-1:2000 |
| Application Note | Optimal dilution of the CD104 antibody should be determined by the researcher. |
| Immunogen | A synthetic peptide specific to human Integrin beta 4 / ITGB4 was used as the immunogen for the CD104 antibody. |
| Purity | Affinity purified |
| Storage | Store the CD104 antibody at -20oC. |
| Limitation | This CD104 antibody is available for research use only. |
| Uniprot # | P16144 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/cd104-antibody-integrin-beta-4-itgb4-aafe-9-rq5468 |
| Title | CD104 Antibody / Integrin beta 4 / ITGB4 |
| Description | Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. The ITGB4 gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. [RefSeq] |
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