NSJ Bioreagents
SKU:R32392
CCT3 Antibody / TCP1 gamma
CCT3 Antibody / TCP1 gamma
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T-complex protein 1 subunit gamma is a protein that in humans is encoded by the CCT3 gene. The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8.
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | 0.5mg/ml if reconstituted with 0.2ml sterile DI water |
| Format | Antigen affinity purified |
| Host Animal | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Species Reactivity | Human, Rat |
| Application | WB, FACS, IHC-P, IF/ICC |
| Application Details | Western blot: 0.1-0.5ug/ml,FACS: 1-3ug/10^6 cells,IHC (FFPE): 1-2ug/ml,IF/ICC (FFPE): 2-4ug/ml |
| Application Note | Optimal dilution of the CCT3 antibody should be determined by the researcher. |
| Localization | Cytoplasmic |
| Immunogen | Amino acids EPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQ were used as the immunogen for the CCT3 antibody. |
| Buffer | Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide |
| Purity | Antigen affinity |
| Storage | After reconstitution, the CCT3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing. |
| Limitation | This CCT3 antibody is available for research use only. |
| Gene ID # | 7203.0 |
| Uniprot # | P49368 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/cct3-antibody-tcp1-gamma-r32392 |
| Title | CCT3 Antibody / TCP1 gamma |
| Description | T-complex protein 1 subunit gamma is a protein that in humans is encoded by the CCT3 gene. The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8. |
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