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NSJ Bioreagents
SKU:RQ5182
Cathepsin L/V/K/H Antibody
Cathepsin L/V/K/H Antibody
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Cathepsins are proteases (enzymes that degrade proteins) found in all animals as well as other organisms. There are approximately a dozen members of this family, which are distinguished by their structure, catalytic mechanism, and which proteins they cleave. Most of the members become activated at the low pH found in lysosomes. Thus, the activity of this family lies almost entirely within those organelles. There are, however, exceptions such as cathepsin K, which works extracellularly after secretion by osteoclasts in bone resorption. Cathepsins have a vital role in mammalian cellular turnover. [Wiki]
Specifications
| Family | Primary antibody |
|---|---|
| Formulation | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA |
| Format | Purified |
| Clone | AACD-3 |
| Host Animal | Rabbit |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Species Reactivity | Human, Mouse, Rat |
| Application | WB |
| Application Details | Western blot: 1:500-1:2000 |
| Application Note | Optimal dilution of the Cathepsin L/V/K/H antibody should be determined by the researcher. |
| Immunogen | A synthetic peptide common to human Cathepsin L/V/K/H was used as the immunogen for the Cathepsin L/V/K/H antibody. |
| Purity | Affinity purified |
| Storage | Store the Cathepsin L/V/K/H antibody at -20oC. |
| Limitation | This Cathepsin L/V/K/H antibody is available for research use only. |
| Uniprot # | P07711 |
| Status | Available |
| PDF Link | https://www.nsjbio.com/tds-pdf/cathepsin-lvkh-antibody-aacd-3-rq5182 |
| Title | Cathepsin L/V/K/H Antibody |
| Description | Cathepsins are proteases (enzymes that degrade proteins) found in all animals as well as other organisms. There are approximately a dozen members of this family, which are distinguished by their structure, catalytic mechanism, and which proteins they cleave. Most of the members become activated at the low pH found in lysosomes. Thus, the activity of this family lies almost entirely within those organelles. There are, however, exceptions such as cathepsin K, which works extracellularly after secretion by osteoclasts in bone resorption. Cathepsins have a vital role in mammalian cellular turnover. [Wiki] |
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