• IHC testing of FFPE human gastric cancer with Cathepsin E antibody at 2ug/ml. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.
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NSJ Bioreagents

RQ4472

Cathepsin E Antibody / CTSE

Cathepsin E Antibody / CTSE

$449.00 USD
$449.00 USD
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Cathepsin E is an enzyme that in humans is encoded by the CTSE gene. This gene encodes a member of the A1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme, an aspartic endopeptidase, may be involved in antigen processing and the maturation of secretory proteins. Elevated expression of this gene has been observed in neurodegeneration.

Specifications

Family Primary antibody
Formulation 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format Antigen affinity purified
Host Animal Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Species Reactivity Human, Mouse, Rat
Application WB, IHC-P
Application Details Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml
Application Note Optimal dilution of the Cathepsin E antibody should be determined by the researcher.
Localization Cytoplasmic, membranous
Immunogen Human Cathepsin E recombinant protein (amino acids A150-R393) was used as the immunogen for the Cathepsin E antibody.
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Purity Antigen affinity
Storage After reconstitution, the Cathepsin E antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitation This Cathepsin E antibody is available for research use only.
Uniprot # P14091
Status Available
PDF Link https://www.nsjbio.com/tds-pdf/cathepsin-e-antibody-ctse-rq4472
Title Cathepsin E Antibody / CTSE
Description Cathepsin E is an enzyme that in humans is encoded by the CTSE gene. This gene encodes a member of the A1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme, an aspartic endopeptidase, may be involved in antigen processing and the maturation of secretory proteins. Elevated expression of this gene has been observed in neurodegeneration.
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